Anti-diabetic activities of Hibiscus cannabinus extracts leaves and roots in vitro study


Citation

Zalinah A., . and Zuraida M. K., . and Muhajir H., . and Maznah I., . (2010) Anti-diabetic activities of Hibiscus cannabinus extracts leaves and roots in vitro study. [Proceedings Paper]

Abstract

Hibiscus cannabinus Kenaf is an annual herbaceous crop of the Malvaceae family. This plant is composed of various active components including tannins saponins polyphenolic alkaloid essential oil and steroid has long been prescribed in traditional folk medicine in India and Africa. The aqueous leaf extract of this plant has been demonstrated to be haematically active and anti-oxidative. The underlying mechanisms that account for Kenaf pharmacology and active components however remain to be elucidated. This experiment was conducted to identify the active compounds of H.cannabinus extracts which had an anti-diabetic activity. There were yields of Hibiscus cannabinus extract which are 28.33 80 ethanol leaves extract and 42.23 hot water leaves extract 6.62 80 ethanol extract and 11.95 hot water extract. H.cannabinus extracts enhanced insulin secretion in BRIN BD11 cells higher than Glibenclamide 100uM except 80 ethanol H. cannabinus leaves extract at concentration 1000 ug/ml.


Download File

Full text available from:

Abstract

Hibiscus cannabinus Kenaf is an annual herbaceous crop of the Malvaceae family. This plant is composed of various active components including tannins saponins polyphenolic alkaloid essential oil and steroid has long been prescribed in traditional folk medicine in India and Africa. The aqueous leaf extract of this plant has been demonstrated to be haematically active and anti-oxidative. The underlying mechanisms that account for Kenaf pharmacology and active components however remain to be elucidated. This experiment was conducted to identify the active compounds of H.cannabinus extracts which had an anti-diabetic activity. There were yields of Hibiscus cannabinus extract which are 28.33 80 ethanol leaves extract and 42.23 hot water leaves extract 6.62 80 ethanol extract and 11.95 hot water extract. H.cannabinus extracts enhanced insulin secretion in BRIN BD11 cells higher than Glibenclamide 100uM except 80 ethanol H. cannabinus leaves extract at concentration 1000 ug/ml.

Additional Metadata

[error in script]
Item Type: Proceedings Paper
Additional Information: Available at Perpustakaan Sultan Abdul Samad Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia. TP248.14 I61 2008 Call Number.
AGROVOC Term: Malvaceae
AGROVOC Term: Hibiscus cannabinus
AGROVOC Term: Kenaf
AGROVOC Term: Extraction in chemical analysis
AGROVOC Term: Cell culture
AGROVOC Term: Leaves
AGROVOC Term: Roots
AGROVOC Term: Ethanol
AGROVOC Term: Chemical compounds
AGROVOC Term: Insulin
Geographical Term: MALAYSIA
Depositing User: Ms. Suzila Mohamad Kasim
Last Modified: 24 Apr 2025 05:15
URI: http://webagris.upm.edu.my/id/eprint/13151

Actions (login required)

View Item View Item