Citation
F. J. Al-Saffar, . and S. Ganabadi, . and S. Fakurazi, . and H. Yaakub, . (2009) Response of Channa striatus extract against MIA induced osteoarthritis in the rat. [Proceedings Paper]
Abstract
The objective of his study was to evaluate chondroprotective effect of oral administration of Channa striatus common name Haruan extract against monosodium iodoacetate MIA induced stifle osteoarthritis OA in the rat. Forty adult male Sprague Dawley rats were divided into four groups n 10 each group. Rats in the first and second groups were treated with the extract in a same dose but with two different courses of therapy. Rats in the third group were treated with Celebrex and served as positive control where as the fourth group was treated with normal saline and served as a negative control. Prior to treatment all animals were injected with MIA intra-articularly in their right knee joints to induce OA Evaluation of OA changes in the knees was assessed with the aid of both radiography and histopathology score. Gross and microscopic results revealed curative effects of the extract on the OA joints.
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Abstract
The objective of his study was to evaluate chondroprotective effect of oral administration of Channa striatus common name Haruan extract against monosodium iodoacetate MIA induced stifle osteoarthritis OA in the rat. Forty adult male Sprague Dawley rats were divided into four groups n 10 each group. Rats in the first and second groups were treated with the extract in a same dose but with two different courses of therapy. Rats in the third group were treated with Celebrex and served as positive control where as the fourth group was treated with normal saline and served as a negative control. Prior to treatment all animals were injected with MIA intra-articularly in their right knee joints to induce OA Evaluation of OA changes in the knees was assessed with the aid of both radiography and histopathology score. Gross and microscopic results revealed curative effects of the extract on the OA joints.
Additional Metadata
| Item Type: | Proceedings Paper |
|---|---|
| Additional Information: | 2 tables |
| AGROVOC Term: | Osteoarthritis |
| AGROVOC Term: | Cartilage |
| AGROVOC Term: | Channa striatus |
| AGROVOC Term: | Rats |
| AGROVOC Term: | Oral administration |
| Geographical Term: | MALAYSIA |
| Depositing User: | Ms. Norfaezah Khomsan |
| Last Modified: | 24 Apr 2025 05:27 |
| URI: | http://webagris.upm.edu.my/id/eprint/15790 |
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