The Effect of n-3 Long Chain Polyunsaturated Fatty Acids LC - PUFA on cognitive function development in rats


Citation

T. Hajjar, . and Y. M. Goh, . and M. A. Rajion, . and M. Ebrahim, . and S. Vidyadaran, . and O. Fauziah, . (2009) The Effect of n-3 Long Chain Polyunsaturated Fatty Acids LC - PUFA on cognitive function development in rats. [Proceedings Paper]

Abstract

The n-3 and n-6 polyunsaturated fatty acids PUFA are essential fatty acids acquired from dietary sources. Consumption of n-3 PUFAs benefits learning ability and vision. Studies in animals have shown the harmful effects ofn-3 PUFA deficit on cognition. This report examined the effects of supplementing different n-3 and n-6 levels in the diets and their effects on cognitive function in rats. Sixty male rats randomly allotted into 5 groups of 12 each were used in this study. The rats received experimental diets with different n-6 / n-3 levels. After 10 weeks the rats were tested for their learning ability and spatial memory using the Morris water maze. Results showed that n-3 and n-6 supplemented rats navigated better and remembered the location of the original platform better as compared to control animals. This experiment clearly showed the beneficial effects of n-3 and n-6 PUFA in improving mental ability in rats.


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Abstract

The n-3 and n-6 polyunsaturated fatty acids PUFA are essential fatty acids acquired from dietary sources. Consumption of n-3 PUFAs benefits learning ability and vision. Studies in animals have shown the harmful effects ofn-3 PUFA deficit on cognition. This report examined the effects of supplementing different n-3 and n-6 levels in the diets and their effects on cognitive function in rats. Sixty male rats randomly allotted into 5 groups of 12 each were used in this study. The rats received experimental diets with different n-6 / n-3 levels. After 10 weeks the rats were tested for their learning ability and spatial memory using the Morris water maze. Results showed that n-3 and n-6 supplemented rats navigated better and remembered the location of the original platform better as compared to control animals. This experiment clearly showed the beneficial effects of n-3 and n-6 PUFA in improving mental ability in rats.

Additional Metadata

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Item Type: Proceedings Paper
Additional Information: 1 tables
AGROVOC Term: Fatty acids
AGROVOC Term: Rats
AGROVOC Term: Polyunsaturated fatty acids
AGROVOC Term: Cognitive learning
AGROVOC Term: Learning ability
Geographical Term: MALAYSIA
Depositing User: Ms. Norfaezah Khomsan
Last Modified: 24 Apr 2025 05:27
URI: http://webagris.upm.edu.my/id/eprint/15812

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