An isolation of chemical compounds and antibacterial activity of the N-hexane fraction of Garcinia nervosa miq. bark

Berna Elya, . and Muhammad Hanafi, . and Ika Mustika, . (2001) An isolation of chemical compounds and antibacterial activity of the N-hexane fraction of Garcinia nervosa miq. bark. [Proceedings Paper]

Garcinia nervosa Miq. is a plant that grows in various parts of Indonesia especially Sumatra Jawa and Kalimantan. The plants usually are utilized as medicines for anti diarrhoea anto-inflammation anti-microbial and skin infection. The isolation was conducted through chromatography using silica gel as stationary phase and n-hexane-ethyl acetate as mobile phase. The structure of isolated compounds were established by spectroscopic data IR H-NMR C-NMR MS. The antibacterial assay used the diffusion method by observing the inhibition zone that was created. Two isolated constituens were identified as stigmasterol C29H50OA and Dulxanthon GC22H22O8B. Antibacterial assay showed that compound B had zone inhibition on growth of Staphylococcus aureus and Eschericia coli.

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Abstract

Garcinia nervosa Miq. is a plant that grows in various parts of Indonesia especially Sumatra Jawa and Kalimantan. The plants usually are utilized as medicines for anti diarrhoea anto-inflammation anti-microbial and skin infection. The isolation was conducted through chromatography using silica gel as stationary phase and n-hexane-ethyl acetate as mobile phase. The structure of isolated compounds were established by spectroscopic data IR H-NMR C-NMR MS. The antibacterial assay used the diffusion method by observing the inhibition zone that was created. Two isolated constituens were identified as stigmasterol C29H50OA and Dulxanthon GC22H22O8B. Antibacterial assay showed that compound B had zone inhibition on growth of Staphylococcus aureus and Eschericia coli.

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Item Type:	Proceedings Paper
Additional Information:	Perpustakaan Sultan Abdul Samad Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia. QD415 A1N277 2000
AGROVOC Term:	GARCINIA
AGROVOC Term:	CHEMICAL COMPOSITION
AGROVOC Term:	ANTIMICROBIAL PROPERTIES
AGROVOC Term:	MEDICINAL PROPERTIES
AGROVOC Term:	ISOLATION
AGROVOC Term:	INDONESIA
Geographical Term:	MALAYSIA
Depositing User:	Ms. Norfaezah Khomsan
Last Modified:	24 Apr 2025 05:27
URI:	http://webagris.upm.edu.my/id/eprint/15915

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