Citation
Luqman Chuah A., . and Pin K. Y., . and Nazira M., . and Mohd Farhan A. R., . and Zamree M. S., . Optimisation of solid liquid extraction of Orthosiphon stamineus leaves using response surface methodology technique. pp. 259-270. ISSN PertanikaJ.Trop.Agric.Sci.38(2):259-270(2015)ISSN:1511-3701
Abstract
Orthosiphon stamineus is one of the popular medicinal plants in Southeast Asia. O. stamineus leaves are used in numerous applications related to medicinal purposes and are believed to cure certain health conditions such as hypertension gout and fever. The aim of this study was to investigate the effect of three parameters involved in extraction process including extraction temperature extraction duration and solvent to solid ratio on extraction yield antioxidant activity and referral markers of O. stamineus leaves. The optimisation of extraction processes was evaluated with the aid of Design-Expert software using response surface methodology (RSM). The optimum extraction parameter for O. stamineus leaves were recorded at the extraction temperature of 60C 30:1 (ml:g) solvent to solid ratio and 6 hours extraction duration with 30Wt extract 67 and 1 mg/L concentration of Rosmarinic acid and Sinensetin respectively. Antioxidant activity for optimized extract is 96.56 and 91.51 of SOD and DPPH method respectively.
Download File
Full text available from:
Official URL: http://pertanika/Pertanika%20PAPERS/JTAS%20Vol.%20...
|
Abstract
Orthosiphon stamineus is one of the popular medicinal plants in Southeast Asia. O. stamineus leaves are used in numerous applications related to medicinal purposes and are believed to cure certain health conditions such as hypertension gout and fever. The aim of this study was to investigate the effect of three parameters involved in extraction process including extraction temperature extraction duration and solvent to solid ratio on extraction yield antioxidant activity and referral markers of O. stamineus leaves. The optimisation of extraction processes was evaluated with the aid of Design-Expert software using response surface methodology (RSM). The optimum extraction parameter for O. stamineus leaves were recorded at the extraction temperature of 60C 30:1 (ml:g) solvent to solid ratio and 6 hours extraction duration with 30Wt extract 67 and 1 mg/L concentration of Rosmarinic acid and Sinensetin respectively. Antioxidant activity for optimized extract is 96.56 and 91.51 of SOD and DPPH method respectively.
Additional Metadata
| Item Type: | Article |
|---|---|
| AGROVOC Term: | Optimization methods |
| AGROVOC Term: | Extraction |
| AGROVOC Term: | Antioxidants |
| AGROVOC Term: | Medicinal plants |
| AGROVOC Term: | Lamiaceae |
| AGROVOC Term: | Solvents |
| AGROVOC Term: | Ethanol |
| AGROVOC Term: | Temperature |
| Geographical Term: | Malaysia |
| Depositing User: | Ms. Suzila Mohamad Kasim |
| Last Modified: | 26 Apr 2025 15:19 |
| URI: | http://webagris.upm.edu.my/id/eprint/21645 |
Actions (login required)
 |
View Item |
