Class 1 integron and associated gene cassettes mediating multiple-drug resistance in some food borne pathogens

Abd El Hamid M. I., . and Attia A. M., . and El-Demerdash A. S., . and Ammar A. M., . and Abd El-Aziz N. K., . Class 1 integron and associated gene cassettes mediating multiple-drug resistance in some food borne pathogens. pp. 332-339. ISSN 2231-7546

The emergence of antibiotic resistance among food borne pathogens has become a serious problem worldwide. The present study reports antibiotic resistance profile of some food borne bacterial pathogens recovered from retail meat of bovine origin and their relevant resistance genes carried on class I integron in Egypt. Thirty-two Escherichia coli 15 salmonella and 25 Staphylococcus aureus isolates were assayed for their antimicrobial susceptibilities. Frequent resistances to amoxicillin-clavulanic acid and erythromycin were observed in E. coli and Salmonella species. Moreover all S. aureus isolates were methicillin-resistant and 52 of the isolates were resistant to each of clindamycin and amoxicillin-clavulanic acid. This is the first report of the comprehensive identification and confirmation of vancomycin resistant S. aureus (VRSA) from meat specimens in Egypt. Interestingly 31.25 40 and 48 of E. coli Salmonella species and S. aureus exhibited features of MDR respectively. Class 1 integrons were commonly found in 66.67 and 50 of MDR salmonella and E. coli respectively; while VRSA isolates were negative. Three different gene cassette arrays encoding resistance to aminoglycoside (aadA2) beta- lactames (blaPSE1) and trimethoprim and aminoglycosides (dfrA15- aadA1) were characterized among the integrase-positive strains. These findings illustrated the role of retail meat as a potential source for the dissemination of MDR E. coli salmonella and VRSA in Egypt.

Full text available from: Official URL: http://www.ifrj.upm.edu.my/23%20(01)%202016/(49).p...

Abstract

The emergence of antibiotic resistance among food borne pathogens has become a serious problem worldwide. The present study reports antibiotic resistance profile of some food borne bacterial pathogens recovered from retail meat of bovine origin and their relevant resistance genes carried on class I integron in Egypt. Thirty-two Escherichia coli 15 salmonella and 25 Staphylococcus aureus isolates were assayed for their antimicrobial susceptibilities. Frequent resistances to amoxicillin-clavulanic acid and erythromycin were observed in E. coli and Salmonella species. Moreover all S. aureus isolates were methicillin-resistant and 52 of the isolates were resistant to each of clindamycin and amoxicillin-clavulanic acid. This is the first report of the comprehensive identification and confirmation of vancomycin resistant S. aureus (VRSA) from meat specimens in Egypt. Interestingly 31.25 40 and 48 of E. coli Salmonella species and S. aureus exhibited features of MDR respectively. Class 1 integrons were commonly found in 66.67 and 50 of MDR salmonella and E. coli respectively; while VRSA isolates were negative. Three different gene cassette arrays encoding resistance to aminoglycoside (aadA2) beta- lactames (blaPSE1) and trimethoprim and aminoglycosides (dfrA15- aadA1) were characterized among the integrase-positive strains. These findings illustrated the role of retail meat as a potential source for the dissemination of MDR E. coli salmonella and VRSA in Egypt.

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Item Type:	Article
AGROVOC Term:	Pathogens
AGROVOC Term:	Antibiotic resistance
AGROVOC Term:	Escherichia coli
AGROVOC Term:	Salmonella
AGROVOC Term:	Staphylococcus aureus
AGROVOC Term:	Foodborne diseases
AGROVOC Term:	Drug resistance
Depositing User:	Ms. Suzila Mohamad Kasim
Last Modified:	24 Apr 2025 06:27
URI:	http://webagris.upm.edu.my/id/eprint/22497

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