Phytochemical screening and antioxidant activity of Melastoma malabathricum and Chromolaena odorata by DPPH radical scavenging method


Citation

Ismail N.H., . and Amira N.H., . and Latip S.N.H.M., . and Zain W.Z.W.M., . and Aani S.N.A., . and Aziman N.A., . (2021) Phytochemical screening and antioxidant activity of Melastoma malabathricum and Chromolaena odorata by DPPH radical scavenging method. Food Research (Malaysia), 5 (S4). pp. 30-37. ISSN 2550-2166

Abstract

Melastoma malabathricum and Chromolaena odorata are classified under broad-leaved weeds that are widely spread in the open land area. Melastoma malabathricum is commonly known as ‘‘senduduk’’, and C. odorata is locally known as “Pokok Kapal Terbang”. Both weeds are categorized as potential weeds as they have high nutritive value and are rich in chemical compounds. This study aimed to determine their chemical constituents and possible potential for antioxidant activity as these weeds have been reported to possess antioxidant properties. Screening of the plants was performed using standard methods and revealed the existence of various secondary metabolites such as saponins, terpenoids, phenols, tannins, and flavonoids of both weed extracts. Antioxidant activity was validated by the DPPH radical scavenging assay of M. malabathricum and C. odorata crude ethanol extract. The IC50 values for the percentage radical scavenging effects for the extracts were determined. The IC50 value of M. malabatrichum extract was 81.116 μg/mL, C. odorata was 312.903 μg/mL, Vitamin C was 31.023 μg/mL and BHA was 71.521 μg/mL respectively. The study showed that the antioxidant activity of M. malabatrichum was more potent and better than C. odorata.


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Abstract

Melastoma malabathricum and Chromolaena odorata are classified under broad-leaved weeds that are widely spread in the open land area. Melastoma malabathricum is commonly known as ‘‘senduduk’’, and C. odorata is locally known as “Pokok Kapal Terbang”. Both weeds are categorized as potential weeds as they have high nutritive value and are rich in chemical compounds. This study aimed to determine their chemical constituents and possible potential for antioxidant activity as these weeds have been reported to possess antioxidant properties. Screening of the plants was performed using standard methods and revealed the existence of various secondary metabolites such as saponins, terpenoids, phenols, tannins, and flavonoids of both weed extracts. Antioxidant activity was validated by the DPPH radical scavenging assay of M. malabathricum and C. odorata crude ethanol extract. The IC50 values for the percentage radical scavenging effects for the extracts were determined. The IC50 value of M. malabatrichum extract was 81.116 μg/mL, C. odorata was 312.903 μg/mL, Vitamin C was 31.023 μg/mL and BHA was 71.521 μg/mL respectively. The study showed that the antioxidant activity of M. malabatrichum was more potent and better than C. odorata.

Additional Metadata

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Item Type: Article
Additional Information: 2nd International Plantation Conference (IPC2021)
AGROVOC Term: Chromolaena odorata
AGROVOC Term: weeds
AGROVOC Term: secondary metabolites
AGROVOC Term: phenols
AGROVOC Term: flavonoids
AGROVOC Term: free radicals
AGROVOC Term: Antioxidants
Geographical Term: Malaysia
Depositing User: Mr. Khoirul Asrimi Md Nor
Date Deposited: 29 Jan 2026 01:55
Last Modified: 29 Jan 2026 01:55
URI: http://webagris.upm.edu.my/id/eprint/3311

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