Japanese encephalitis virus: epidemiological studies in man in Penang island


Citation

Asiah N. M., . and Fazehah B., . and Sharifah H., . and Cardosa M. K., . Japanese encephalitis virus: epidemiological studies in man in Penang island. pp. 27-31. ISSN 0128-2506

Abstract

Human blood donors from Penang Hospital were tested for a period of one year for Japanese encephalitis (JE) virus positive reactors. The presence of specific IgG against dengue virus (DEN) and JE virus were determined by the dot enzyme immunoassay (DEIA) test. Approximately 79 were flavivirus positive while 8.2 had a stronger antibody response to JEV than DEN. About 6.5 of the total serum tested (8 080) were found to have been exposed to JEV. The plaque reduction neutralisation test (PRNT) titres on 10 sera with higher titres to dengue as compared to JEV showed high correlating dengue PRNT titres and low JEV PRNT titres. However PRNT on 10 of the sera that were highly positive to JEV than to DEN resulted in only 20 having high titres to JEV as compared to dengue 62 having high titres to dengue as compared to JEV and 18 having equal titres to JEV and dengue. About 1.3 of the samples tested have shown a likelihood of exposure to JEV.


Download File

Full text available from:

Abstract

Human blood donors from Penang Hospital were tested for a period of one year for Japanese encephalitis (JE) virus positive reactors. The presence of specific IgG against dengue virus (DEN) and JE virus were determined by the dot enzyme immunoassay (DEIA) test. Approximately 79 were flavivirus positive while 8.2 had a stronger antibody response to JEV than DEN. About 6.5 of the total serum tested (8 080) were found to have been exposed to JEV. The plaque reduction neutralisation test (PRNT) titres on 10 sera with higher titres to dengue as compared to JEV showed high correlating dengue PRNT titres and low JEV PRNT titres. However PRNT on 10 of the sera that were highly positive to JEV than to DEN resulted in only 20 having high titres to JEV as compared to dengue 62 having high titres to dengue as compared to JEV and 18 having equal titres to JEV and dengue. About 1.3 of the samples tested have shown a likelihood of exposure to JEV.

Additional Metadata

[error in script]
Item Type: Article
AGROVOC Term: Japanese encephalitis virus
AGROVOC Term: Epidemiology
AGROVOC Term: Disease prevalence
AGROVOC Term: Infection
AGROVOC Term: Antibodies
AGROVOC Term: Antigens
AGROVOC Term: Blood sampling
AGROVOC Term: EIA (enzyme immunoassay)
AGROVOC Term: Neutralization tests
AGROVOC Term: Neutralization
Depositing User: Mr. AFANDI ABDUL MALEK
Last Modified: 24 Apr 2025 00:54
URI: http://webagris.upm.edu.my/id/eprint/8665

Actions (login required)

View Item View Item