Citation
Nachimutu K., . and Masillamony P. R., . and Padmanaban V. D., . Role of B cells T cells and macrophages in the immune response of chicks to Newcastle disease virus. pp. 25-31. ISSN 9128-2506
Abstract
Two groups of chicks were immunosuppressed by thymectomy or bursectomy followed by antithymus serum and antibursal serum treatment. The thirt group of chicks were immunosuppressed by cyclo-phosphamide and antibursal serum treatment. Carrageenan treatment was undertaken with the fourth group of chicks to impair the macrophage function. These chicks were vaccinated at weekly intervals starting from the 10th day to 59th day of age. After assessing the humoral and cell mediated immune response the chicks were challenged at weekly intervals to assess the protection per cent to Newcastle disease virus. It was found that in thymectomised vaccinated chicks the protection was 64.2 in bursectomized vaccinated chicks the protection was 52.4 and the balance of 16.6 protection appeared to be due to the interaction of B cells T cells and macrophage in chicks vaccinated with La Sota strain of Newcaste disease virus.
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Abstract
Two groups of chicks were immunosuppressed by thymectomy or bursectomy followed by antithymus serum and antibursal serum treatment. The thirt group of chicks were immunosuppressed by cyclo-phosphamide and antibursal serum treatment. Carrageenan treatment was undertaken with the fourth group of chicks to impair the macrophage function. These chicks were vaccinated at weekly intervals starting from the 10th day to 59th day of age. After assessing the humoral and cell mediated immune response the chicks were challenged at weekly intervals to assess the protection per cent to Newcastle disease virus. It was found that in thymectomised vaccinated chicks the protection was 64.2 in bursectomized vaccinated chicks the protection was 52.4 and the balance of 16.6 protection appeared to be due to the interaction of B cells T cells and macrophage in chicks vaccinated with La Sota strain of Newcaste disease virus.
Additional Metadata
| Item Type: | Article |
|---|---|
| AGROVOC Term: | Chicks |
| AGROVOC Term: | Chickens |
| AGROVOC Term: | Poultry |
| AGROVOC Term: | Immune response |
| AGROVOC Term: | Immunosuppression |
| AGROVOC Term: | Newcastle disease virus |
| AGROVOC Term: | Serum therapy |
| AGROVOC Term: | Infectious bursal disease |
| AGROVOC Term: | Carrageenans |
| AGROVOC Term: | Vaccination |
| Depositing User: | Mr. AFANDI ABDUL MALEK |
| Last Modified: | 24 Apr 2025 00:54 |
| URI: | http://webagris.upm.edu.my/id/eprint/8887 |
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